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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CRKL HGNC:2363 (HGNC)
1399 (Entrez Gene)
602007 (OMIM)
CRKL (MyGene.info)
HGNC homology
Chr22 q11.21 Chr22:20917398-20953749 (+)
P46109 (UniProt | EBI)
NM_005207 (RefSeq)
mouse Crkl MGI:104686 (MGI)
12929 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 10.82 cM Chr16:17451987-17487434 (+)
DiGeorge syndrome
velocardiofacial syndrome
ENSMUSG00000006134 (Ensembl Gene Model)
ENSMUSP00000006293 (Ensembl)
ENSMUST00000006293 (Ensembl)
rat Crkl 287942 (Entrez Gene)
Chr11 q23 Q5U2U2 (UniProt | EBI)
NM_001008284 (RefSeq)
LOC100911248 100911248 (Entrez Gene)
Chr11 XP_003751143 (RefSeq)
chimpanzee CRKL 470146 (Entrez Gene)
dog CRKL 608125 (Entrez Gene)
Chr26 XP_849949 (RefSeq)
chicken CRKL 416939 (Entrez Gene)
Chr15 XP_415233 (RefSeq)
zebrafish crkl 556443 (Entrez Gene)
Chr21 NP_998703 (RefSeq)
NM_213538 (RefSeq)
frog, western clawed crkl 394657 (Entrez Gene)
Chr1 NP_989060 (RefSeq)
NM_203729 (RefSeq)
macaque, rhesus CRKL 696584 (Entrez Gene)
Chr10 NP_001244412 (RefSeq)
NM_001257483 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory