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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRAS HGNC:6407 (HGNC)
3845 (Entrez Gene)
190070 (OMIM)
HGNC homology
Chr12 p12.1 Chr12:25204789-25252093 (-)
Bladder Cancer
Breast Cancer
Cardiofaciocutaneous Syndrome 2; CFC2
Gastric Cancer, Hereditary Diffuse; HDGC
Leukemia, Acute Myeloid; AML
Lung Cancer
Noonan Syndrome 3; NS3
Pancreatic Cancer
Schimmelpenning-Feuerstein-Mims Syndrome; SFM
P01116 (UniProt | EBI)
NM_033360 (RefSeq)
mouse Kras MGI:96680 (MGI)
16653 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 77.37 cM Chr6:145216699-145250239 (-)
Endometriosis, Susceptibility to, 1
Juvenile Myelomonocytic Leukemia; JMML
Lung Cancer
Lung Cancer Susceptibility 3; LNCR3
Noonan Syndrome 3; NS3
Pancreatic Cancer
Prostate Cancer
OTTMUSG00000022179 (VEGA)
OTTMUSP00000025007 (VEGA)
OTTMUST00000052667 (VEGA)
rat Kras 24525 (Entrez Gene)
Chr4 q44 P08644 (UniProt | EBI)
NM_031515 (RefSeq)
chimpanzee KRAS 473387 (Entrez Gene)
Chr12 XP_003313842 (RefSeq)
cattle KRAS 541140 (Entrez Gene)
Chr5 NP_001103471 (RefSeq)
NM_001110001 (RefSeq)
dog KRAS 403871 (Entrez Gene)
Chr27 XP_003433609 (RefSeq)
chicken KRAS 418207 (Entrez Gene)
Chr1 NP_001243091 (RefSeq)
NM_001256162 (RefSeq)
zebrafish kras 445289 (Entrez Gene)
Chr25 NP_001003744 (RefSeq)
NM_001003744 (RefSeq)
frog, western clawed LOC100485959 100485959 (Entrez Gene)
ChrUN XP_004920180 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory