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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37990

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRAS HGNC:6407 (HGNC)
3845 (Entrez Gene)
190070 (OMIM)
Chr12 p12.1 Chr12:25205246-25250923 (-)
GRCh38
Bladder Cancer
Breast Cancer
Cardiofaciocutaneous Syndrome 2; CFC2
Gastric Cancer, Hereditary Diffuse; HDGC
Lung Cancer
Noonan Syndrome 3; NS3
Pancreatic Cancer
Schimmelpenning-Feuerstein-Mims Syndrome; SFM
P01116 (UniProt | EBI)
NM_004985 (RefSeq)
mouse Kras MGI:96680 (MGI)
16653 (Entrez Gene)
Gene Tree
VISTA-Point
Chr6 77.37 cM Chr6:145216699-145250239 (-)
GRCm38
Colorectal Cancer; CRC
Endometriosis, Susceptibility to, 1
Juvenile Myelomonocytic Leukemia; JMML
Lung Cancer
Lung Cancer Susceptibility 3; LNCR3
Neurofibromatosis, Type I; NF1
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer
OTTMUSG00000022179 (VEGA)
OTTMUSP00000025007 (VEGA)
OTTMUST00000052667 (VEGA)
rat Kras 24525 (Entrez Gene)
Chr4 q44 P08644 (UniProt | EBI)
NM_031515 (RefSeq)
chimpanzee KRAS 473387 (Entrez Gene)
Chr12 XP_528758 (RefSeq)
cattle KRAS 541140 (Entrez Gene)
Chr5 NP_001103471 (RefSeq)
NM_001110001 (RefSeq)
dog KRAS 403871 (Entrez Gene)
Chr27 XP_003433608 (RefSeq)
chicken KRAS 418207 (Entrez Gene)
Chr1 NP_001243091 (RefSeq)
NM_001256162 (RefSeq)
western clawed frog LOC100485959 100485959 (Entrez Gene)
ChrUN XP_002943663 (RefSeq)
zebrafish kras 445289 (Entrez Gene)
Chr25 NP_001003744 (RefSeq)
NM_001003744 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory