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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRAS HGNC:6407 (HGNC)
3845 (Entrez Gene)
190070 (OMIM)
KRAS (MyGene.info)
HGNC homology
Chr12 p12.1 Chr12:25204789-25252093 (-)
acute myeloid leukemia
arteriovenous malformations of the brain
autoimmune lymphoproliferative syndrome type 4
breast cancer
cardiofaciocutaneous syndrome
lung cancer
Noonan syndrome 3
pancreatic carcinoma
stomach cancer
urinary bladder cancer
P01116 (UniProt | EBI)
NM_001369787 (RefSeq)
mouse Kras MGI:96680 (MGI)
16653 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 77.37 cM Chr6:145216699-145250239 (-)
intrahepatic cholangiocarcinoma
juvenile myelomonocytic leukemia
lung cancer
Noonan syndrome 3
pancreatic carcinoma
prostate cancer
ENSMUSG00000030265 (Ensembl Gene Model)
ENSMUSP00000107339 (Ensembl)
ENSMUST00000111710 (Ensembl)
rat Kras 24525 (Entrez Gene)
Chr4 q44 P08644 (UniProt | EBI)
NM_031515 (RefSeq)
chimpanzee KRAS 473387 (Entrez Gene)
Chr12 XP_009423991 (RefSeq)
cattle KRAS 541140 (Entrez Gene)
Chr5 NP_001103471 (RefSeq)
NM_001110001 (RefSeq)
dog KRAS 403871 (Entrez Gene)
Chr27 XP_013963974 (RefSeq)
chicken KRAS 418207 (Entrez Gene)
Chr1 NP_001243091 (RefSeq)
NM_001256162 (RefSeq)
zebrafish kras 445289 (Entrez Gene)
Chr25 NP_001349423 (RefSeq)
NM_001362494 (RefSeq)
frog, western clawed LOC100485959 100485959 (Entrez Gene)
ChrUN XP_004920181 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory