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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TRPC6 HGNC:12338 (HGNC)
7225 (Entrez Gene)
603652 (OMIM)
TRPC6 (MyGene.info)
HGNC homology
Chr11 q22.1 Chr11:101451470-101584018 (-)
focal segmental glomerulosclerosis 2
Q9Y210 (UniProt | EBI)
NM_004621 (RefSeq)
mouse Trpc6 MGI:109523 (MGI)
22068 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 2.46 cM Chr9:8544142-8680741 (+)
focal segmental glomerulosclerosis 2
ENSMUSG00000031997 (Ensembl Gene Model)
ENSMUSP00000057965 (Ensembl)
ENSMUST00000050433 (Ensembl)
rat Trpc6 89823 (Entrez Gene)
Chr8 q11 NP_446011 (RefSeq)
NM_053559 (RefSeq)
chimpanzee TRPC6 451503 (Entrez Gene)
Chr11 XP_016777341 (RefSeq)
cattle TRPC6 407151 (Entrez Gene)
Chr15 Q9MYW0 (UniProt | EBI)
NM_001166572 (RefSeq)
dog TRPC6 489435 (Entrez Gene)
Chr5 XP_546553 (RefSeq)
chicken TRPC6 418989 (Entrez Gene)
Chr1 XP_004938897 (RefSeq)
zebrafish LOC100333090 100333090 (Entrez Gene)
trpc6a 563989 (Entrez Gene)
Chr21 NP_001025453 (RefSeq)
NM_001030282 (RefSeq)
frog, western clawed trpc6 100493327 (Entrez Gene)
Chr2 XP_002935616 (RefSeq)
macaque, rhesus TRPC6 703611 (Entrez Gene)
Chr14 XP_014971021 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory