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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RPS6KA3 HGNC:10432 (HGNC)
6197 (Entrez Gene)
300075 (OMIM)
HGNC homology
ChrX p22.2-p22.1 ChrX:20149911-20267095 (-)
Coffin-Lowry Syndrome; CLS
Mental Retardation, X-Linked 19; MRX19
P51812 (UniProt | EBI)
NM_004586 (RefSeq)
mouse Rps6ka3 MGI:104557 (MGI)
110651 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 73.27 cM ChrX:159210307-159368244 (+)
Coffin-Lowry Syndrome; CLS
OTTMUSG00000016505 (VEGA)
OTTMUSP00000017786 (VEGA)
OTTMUST00000039877 (VEGA)
rat Rps6ka3 501560 (Entrez Gene)
ChrX q21 NP_001178933 (RefSeq)
NM_001192004 (RefSeq)
chimpanzee RPS6KA3 450110 (Entrez Gene)
ChrX XP_009437123 (RefSeq)
rhesus macaque RPS6KA3 696825 (Entrez Gene)
ChrX XP_014982558 (RefSeq)
cattle RPS6KA3 511190 (Entrez Gene)
ChrX NP_001092407 (RefSeq)
NM_001098937 (RefSeq)
dog RPS6KA3 491768 (Entrez Gene)
ChrX XP_013967119 (RefSeq)
chicken RPS6KA3 418605 (Entrez Gene)
Chr1 XP_015128148 (RefSeq)
western clawed frog rps6ka3 100496161 (Entrez Gene)
ChrUN XP_002936090 (RefSeq)
zebrafish rps6ka3b 100009657 (Entrez Gene)
Chr24 NP_001076495 (RefSeq)
NM_001083026 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory