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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EZH2 HGNC:3527 (HGNC)
2146 (Entrez Gene)
601573 (OMIM)
EZH2 (MyGene.info)
HGNC homology
Chr7 q36.1 Chr7:148807372-148884662 (-)
Weaver syndrome
Q15910 (UniProt | EBI)
NM_004456 (RefSeq)
mouse Ezh2 MGI:107940 (MGI)
14056 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 22.92 cM Chr6:47530139-47595341 (-)
acute lymphocytic leukemia
OTTMUSG00000021193 (VEGA)
OTTMUSP00000023406 (VEGA)
OTTMUST00000050207 (VEGA)
rat Ezh2 312299 (Entrez Gene)
Chr4 q24 NP_001128451 (RefSeq)
NM_001134979 (RefSeq)
chimpanzee EZH2 745437 (Entrez Gene)
Chr7 XP_016813835 (RefSeq)
cattle EZH2 509106 (Entrez Gene)
Chr4 NP_001179953 (RefSeq)
NM_001193024 (RefSeq)
dog EZH2 475511 (Entrez Gene)
Chr16 XP_005629576 (RefSeq)
chicken EZH2 420784 (Entrez Gene)
Chr2 XP_015131398 (RefSeq)
zebrafish ezh2 768133 (Entrez Gene)
Chr24 Q08BS4 (UniProt | EBI)
NM_001040292 (RefSeq)
frog, western clawed ezh2 550047 (Entrez Gene)
Chr6 Q28D84 (UniProt | EBI)
NM_001017293 (RefSeq)
macaque, rhesus EZH2 709075 (Entrez Gene)
Chr3 NP_001253432 (RefSeq)
NM_001266503 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory