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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37926

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EZH2 HGNC:3527 (HGNC)
2146 (Entrez Gene)
601573 (OMIM)
Chr7 q35-q36 Chr7:148807372-148884349 (-)
GRCh38
Weaver Syndrome; WVS
Q15910 (UniProt | EBI)
NM_004456 (RefSeq)
mouse Ezh2 MGI:107940 (MGI)
14056 (Entrez Gene)
Gene Tree
VISTA-Point
Chr6 22.92 cM Chr6:47530274-47595341 (-)
GRCm38
Leukemia, Acute Lymphoblastic; ALL
OTTMUSG00000021193 (VEGA)
OTTMUSP00000023406 (VEGA)
OTTMUST00000050207 (VEGA)
rat Ezh2 312299 (Entrez Gene)
Chr4 q24 NP_001128451 (RefSeq)
NM_001134979 (RefSeq)
chimpanzee EZH2 745437 (Entrez Gene)
Chr7 XP_001165949 (RefSeq)
rhesus macaque EZH2 709075 (Entrez Gene)
Chr3 NP_001253432 (RefSeq)
NM_001266503 (RefSeq)
cattle EZH2 509106 (Entrez Gene)
Chr4 NP_001179953 (RefSeq)
NM_001193024 (RefSeq)
dog EZH2 475511 (Entrez Gene)
Chr16 XP_003432121 (RefSeq)
chicken EZH2 420784 (Entrez Gene)
Chr2 XP_418879 (RefSeq)
western clawed frog ezh2 550047 (Entrez Gene)
ChrUN Q28D84 (UniProt | EBI)
NM_001017293 (RefSeq)
zebrafish ezh2 768133 (Entrez Gene)
Chr24 Q08BS4 (UniProt | EBI)
NM_001040292 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory