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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DSP HGNC:3052 (HGNC)
1832 (Entrez Gene)
125647 (OMIM)
Desmoplakin (MyGene.info)
HGNC homology
Chr6 p24.3 Chr6:7541575-7586717 (+)
arrhythmogenic right ventricular dysplasia 8
dilated cardiomyopathy with woolly hair and keratoderma
P15924 (UniProt | EBI)
NM_004415 (RefSeq)
mouse Dsp MGI:109611 (MGI)
109620 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 18.0 cM Chr13:38151328-38198577 (+)
arrhythmogenic right ventricular dysplasia 8
OTTMUSG00000032599 (VEGA)
OTTMUSP00000043295 (VEGA)
OTTMUST00000081065 (VEGA)
rat Dsp 306871 (Entrez Gene)
Chr17 p12 XP_017456202 (RefSeq)
chimpanzee DSP 462420 (Entrez Gene)
Chr6 XP_001165361 (RefSeq)
cattle DSP 514360 (Entrez Gene)
Chr23 NP_001179297 (RefSeq)
NM_001192368 (RefSeq)
dog DSP 488207 (Entrez Gene)
Chr35 XP_545329 (RefSeq)
chicken DSP 420869 (Entrez Gene)
Chr2 XP_004939722 (RefSeq)
zebrafish dspa 324023 (Entrez Gene)
Chr2 XP_001919901 (RefSeq)
macaque, rhesus DSP 694860 (Entrez Gene)
Chr4 XP_001085012 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.10
The Jackson Laboratory