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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DSP HGNC:3052 (HGNC)
1832 (Entrez Gene)
125647 (OMIM)
Chr6 p24 Chr6:7541637-7586713 (+)
Arrhythmogenic Right Ventricular Dysplasia, Familial, 8; ARVD8
Cardiomyopathy, Dilated, with Woolly Hair and Keratoderma; DCWHK
Cardiomyopathy, Dilated, with Woolly Hair, Keratoderma, and Tooth Agenesis; DCWHKTA
Epidermolysis Bullosa, Lethal Acantholytic; EBLA
Keratosis Palmoplantaris Striata II; PPKS2
Skin Fragility-Woolly Hair Syndrome; SFWHS
P15924 (UniProt | EBI)
NM_001008844 (RefSeq)
mouse Dsp MGI:109611 (MGI)
109620 (Entrez Gene)
Gene Tree
Chr13 18.0 cM Chr13:35876925-43767806
Cardiomyopathy, Dilated, with Woolly Hair and Keratoderma; DCWHK
OTTMUSG00000032599 (VEGA)
OTTMUSP00000043295 (VEGA)
OTTMUST00000081065 (VEGA)
rat Dsp 306871 (Entrez Gene)
Chr17 p12 XP_001058477 (RefSeq)
chimpanzee DSP 462420 (Entrez Gene)
Chr6 XP_001165361 (RefSeq)
rhesus macaque DSP 694860 (Entrez Gene)
Chr4 XP_001084900 (RefSeq)
cattle DSP 514360 (Entrez Gene)
Chr23 NP_001179297 (RefSeq)
NM_001192368 (RefSeq)
dog DSP 488207 (Entrez Gene)
Chr35 XP_545329 (RefSeq)
chicken DSP 420869 (Entrez Gene)
Chr2 XP_001231411 (RefSeq)
zebrafish dspa 324023 (Entrez Gene)
Chr2 XP_001919901 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory