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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
379

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PCSK1 HGNC:8743 (HGNC)
5122 (Entrez Gene)
162150 (OMIM)
Chr5 q15-q21 Chr5:96390336-96433281 (-)
GRCh38
Proprotein Convertase 1/3 Deficiency
P29120 (UniProt | EBI)
NM_000439 (RefSeq)
mouse Pcsk1 MGI:97511 (MGI)
18548 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 40.63 cM Chr13:75089826-75132498 (+)
GRCm38
Obesity
OTTMUSG00000026053 (VEGA)
OTTMUSP00000031918 (VEGA)
OTTMUST00000064311 (VEGA)
chimpanzee PCSK1 461740 (Entrez Gene)
Chr5 XP_001134900 (RefSeq)
rhesus macaque PCSK1 699742 (Entrez Gene)
Chr6 XP_002804496 (RefSeq)
cattle PCSK1 281967 (Entrez Gene)
Chr7 Q9GLR1 (UniProt | EBI)
NM_174412 (RefSeq)
dog PCSK1 479149 (Entrez Gene)
Chr3 XP_848637 (RefSeq)
chicken PCSK1 769230 (Entrez Gene)
ChrZ XP_003643108 (RefSeq)
western clawed frog pcsk1 100496933 (Entrez Gene)
ChrUN XP_002933476 (RefSeq)
zebrafish pcsk1 100005716 (Entrez Gene)
Chr21 NP_001131134 (RefSeq)
NM_001137662 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory