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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PCSK1 HGNC:8743 (HGNC)
5122 (Entrez Gene)
162150 (OMIM)
Proprotein convertase 1 (MyGene.info)
HGNC homology
Chr5 q15 Chr5:96390336-96433281 (-)
P29120 (UniProt | EBI)
NM_000439 (RefSeq)
mouse Pcsk1 MGI:97511 (MGI)
18548 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 40.63 cM Chr13:75089826-75134861 (+)
ENSMUSG00000021587 (Ensembl Gene Model)
ENSMUSP00000022075 (Ensembl)
ENSMUST00000022075 (Ensembl)
chimpanzee PCSK1 461740 (Entrez Gene)
Chr5 XP_003310699 (RefSeq)
cattle PCSK1 281967 (Entrez Gene)
Chr7 Q9GLR1 (UniProt | EBI)
NM_174412 (RefSeq)
dog PCSK1 479149 (Entrez Gene)
Chr3 XP_848637 (RefSeq)
chicken PCSK1 769230 (Entrez Gene)
ChrZ XP_003643108 (RefSeq)
zebrafish pcsk1 100005716 (Entrez Gene)
Chr21 NP_001131134 (RefSeq)
NM_001137662 (RefSeq)
frog, western clawed pcsk1 100496933 (Entrez Gene)
Chr1 XP_017946284 (RefSeq)
macaque, rhesus PCSK1 699742 (Entrez Gene)
Chr6 XP_028705415 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory