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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AKT1 HGNC:391 (HGNC)
207 (Entrez Gene)
164730 (OMIM)
AKT1 (MyGene.info)
HGNC homology
Chr14 q32.33 Chr14:104769349-104795743 (-)
breast cancer
colorectal cancer
Cowden disease
ovarian cancer
Proteus syndrome
P31749 (UniProt | EBI)
NM_001014431 (RefSeq)
mouse Akt1 MGI:87986 (MGI)
11651 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 61.2 cM Chr12:112653821-112674884 (-)
OTTMUSG00000020941 (VEGA)
OTTMUSP00000022944 (VEGA)
OTTMUST00000049495 (VEGA)
rat Akt1 24185 (Entrez Gene)
Chr6 q32 P47196 (UniProt | EBI)
NM_033230 (RefSeq)
chimpanzee AKT1 740898 (Entrez Gene)
Chr14 XP_024204727 (RefSeq)
cattle AKT1 280991 (Entrez Gene)
Chr21 Q01314 (UniProt | EBI)
NM_173986 (RefSeq)
dog AKT1 490878 (Entrez Gene)
Chr8 XP_022278130 (RefSeq)
chicken AKT1 395928 (Entrez Gene)
Chr5 NP_990386 (RefSeq)
NM_205055 (RefSeq)
zebrafish LOC100331515 100331515 (Entrez Gene)
frog, western clawed akt1 100490038 (Entrez Gene)
Chr8 XP_002940763 (RefSeq)
macaque, rhesus AKT1 697747 (Entrez Gene)
Chr7 NP_001248554 (RefSeq)
NM_001261625 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory