About   Help   FAQ
HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human SPR HGNC:11257 (HGNC)
6697 (Entrez Gene)
182125 (OMIM)
Sepiapterin reductase (MyGene.info)
HGNC homology
Chr2 p13.2 Chr2:72887383-72892160 (+)
sepiapterin reductase deficiency
P35270 (UniProt | EBI)
NM_003124 (RefSeq)
mouse Spr MGI:103078 (MGI)
20751 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 37.15 cM Chr6:85130176-85137766 (-)
Parkinson's disease
OTTMUSG00000037795 (VEGA)
OTTMUSP00000054720 (VEGA)
OTTMUST00000097538 (VEGA)
rat Spr 29270 (Entrez Gene)
Chr4 q34 P18297 (UniProt | EBI)
NM_019181 (RefSeq)
chimpanzee SPR 470403 (Entrez Gene)
Chr2A XP_016804250 (RefSeq)
cattle SPR 533836 (Entrez Gene)
Chr11 Q17QK8 (UniProt | EBI)
NM_001076003 (RefSeq)
dog SPR 483118 (Entrez Gene)
Chr17 XP_540234 (RefSeq)
chicken SPR 425255 (Entrez Gene)
Chr4 XP_423038 (RefSeq)
zebrafish spra 554136 (Entrez Gene)
Chr5 NP_001019601 (RefSeq)
NM_001024430 (RefSeq)
sprb 795445 (Entrez Gene)
Chr8 NP_001122262 (RefSeq)
NM_001128790 (RefSeq)
frog, western clawed spr 100145068 (Entrez Gene)
Chr1 B0BML7 (UniProt | EBI)
NM_001126595 (RefSeq)
macaque, rhesus SPR 705317 (Entrez Gene)
Chr13 NP_001247478 (RefSeq)
NM_001260549 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.12
The Jackson Laboratory