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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PSAP HGNC:9498 (HGNC)
5660 (Entrez Gene)
176801 (OMIM)
Prosaposin (MyGene.info)
HGNC homology
Chr10 q22.1 Chr10:71816283-71851375 (-)
atypical Gaucher's disease due to saposin c deficiency
metachromatic leukodystrophy
P07602 (UniProt | EBI)
NM_001042465 (RefSeq)
mouse Psap MGI:97783 (MGI)
19156 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 30.02 cM Chr10:60277627-60302594 (+)
Krabbe disease
metachromatic leukodystrophy
OTTMUSG00000016474 (VEGA)
OTTMUSP00000017725 (VEGA)
OTTMUST00000039727 (VEGA)
rat Psap 25524 (Entrez Gene)
Chr20 q11 P10960 (UniProt | EBI)
NM_013013 (RefSeq)
chimpanzee PSAP 450517 (Entrez Gene)
Chr10 XP_003312667 (RefSeq)
cattle PSAP 281433 (Entrez Gene)
Chr28 P26779 (UniProt | EBI)
NM_174161 (RefSeq)
dog PSAP 479240 (Entrez Gene)
Chr4 XP_005619049 (RefSeq)
chicken PSAP 395602 (Entrez Gene)
Chr6 O13035 (UniProt | EBI)
NM_204811 (RefSeq)
zebrafish psap 140811 (Entrez Gene)
Chr13 NP_571958 (RefSeq)
NM_131883 (RefSeq)
frog, western clawed psap 550039 (Entrez Gene)
Chr7 NP_001017285 (RefSeq)
NM_001017285 (RefSeq)
macaque, rhesus PSAP 709510 (Entrez Gene)
Chr9 XP_015002912 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory