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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PCSK2 HGNC:8744 (HGNC)
5126 (Entrez Gene)
162151 (OMIM)
Proprotein convertase 2 (MyGene.info)
HGNC homology
Chr20 p12.1 Chr20:17226107-17484578 (+)
P16519 (UniProt | EBI)
NM_001201529 (RefSeq)
mouse Pcsk2 MGI:97512 (MGI)
18549 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 70.89 cM Chr2:143546156-143816285 (+)
ENSMUSG00000027419 (Ensembl Gene Model)
ENSMUSP00000028905 (Ensembl)
ENSMUST00000028905 (Ensembl)
rat Pcsk2 25121 (Entrez Gene)
Chr3 q41 P28841 (UniProt | EBI)
NM_012746 (RefSeq)
chimpanzee PCSK2 458106 (Entrez Gene)
Chr20 XP_001138346 (RefSeq)
cattle PCSK2 281968 (Entrez Gene)
Chr13 Q9GLR0 (UniProt | EBI)
NM_174413 (RefSeq)
dog PCSK2 485757 (Entrez Gene)
Chr24 XP_003433232 (RefSeq)
chicken PCSK2 395136 (Entrez Gene)
Chr3 XP_004940271 (RefSeq)
zebrafish pcsk2 100004460 (Entrez Gene)
Chr13 NP_001135738 (RefSeq)
NM_001142266 (RefSeq)
frog, western clawed pcsk2 100036632 (Entrez Gene)
Chr5 NP_001090660 (RefSeq)
NM_001097191 (RefSeq)
macaque, rhesus PCSK2 695730 (Entrez Gene)
Chr10 NP_001252954 (RefSeq)
NM_001266025 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory