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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
376

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NOTCH3 HGNC:7883 (HGNC)
4854 (Entrez Gene)
600276 (OMIM)
Chr19 p13.2-p13.1 Chr19:15159633-15200981 (-)
GRCh38
Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL
Myofibromatosis, Infantile, 2; IMF2
Q9UM47 (UniProt | EBI)
NM_000435 (RefSeq)
mouse Notch3 MGI:99460 (MGI)
18131 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 17.37 cM Chr17:32120820-32166880 (-)
GRCm38
Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL
OTTMUSG00000030086 (VEGA)
OTTMUSP00000038868 (VEGA)
OTTMUST00000074537 (VEGA)
rat Notch3 56761 (Entrez Gene)
Chr7 q11 Q9R172 (UniProt | EBI)
NM_020087 (RefSeq)
chimpanzee NOTCH3 455792 (Entrez Gene)
Chr19 XP_003316212 (RefSeq)
rhesus macaque NOTCH3 719119 (Entrez Gene)
Chr19 XP_002808222 (RefSeq)
cattle NOTCH3 789485 (Entrez Gene)
Chr7 XP_003582430 (RefSeq)
dog NOTCH3 610439 (Entrez Gene)
Chr20 XP_005633258 (RefSeq)
western clawed frog notch2 100494244 (Entrez Gene)
ChrUN XP_002941531 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory