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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IDH2 HGNC:5383 (HGNC)
3418 (Entrez Gene)
147650 (OMIM)
IDH2 (MyGene.info)
HGNC homology
Chr15 q26.1 Chr15:90083978-90102554 (-)
D-2-hydroxyglutaric aciduria
P48735 (UniProt | EBI)
NM_001289910 (RefSeq)
mouse Idh2 MGI:96414 (MGI)
269951 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 45.43 cM Chr7:80094846-80115392 (-)
OTTMUSG00000024961 (VEGA)
OTTMUSP00000030144 (VEGA)
OTTMUST00000061456 (VEGA)
rat Idh2 361596 (Entrez Gene)
Chr1 q31 P56574 (UniProt | EBI)
NM_001014161 (RefSeq)
chimpanzee IDH2 453645 (Entrez Gene)
Chr15 XP_510589 (RefSeq)
cattle IDH2 327669 (Entrez Gene)
Chr21 Q04467 (UniProt | EBI)
NM_175790 (RefSeq)
dog IDH2 479043 (Entrez Gene)
Chr3 XP_013967907 (RefSeq)
chicken IDH2 431056 (Entrez Gene)
Chr10 NP_001026770 (RefSeq)
NM_001031599 (RefSeq)
zebrafish idh2 386951 (Entrez Gene)
Chr18 NP_955858 (RefSeq)
NM_199564 (RefSeq)
frog, western clawed idh2 448026 (Entrez Gene)
Chr3 NP_001004799 (RefSeq)
NM_001004799 (RefSeq)
macaque, rhesus IDH2 701480 (Entrez Gene)
Chr7 NP_001244691 (RefSeq)
NM_001257762 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory