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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RYR2 HGNC:10484 (HGNC)
6262 (Entrez Gene)
180902 (OMIM)
Ryanodine receptor 2 (MyGene.info)
HGNC homology
Chr1 q43 Chr1:237042208-237833988 (+)
arrhythmogenic right ventricular dysplasia 2
catecholaminergic polymorphic ventricular tachycardia 1
Q92736 (UniProt | EBI)
NM_001035 (RefSeq)
mouse Ryr2 MGI:99685 (MGI)
20191 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 4.38 cM Chr13:11553102-12106945 (-)
arrhythmogenic right ventricular dysplasia 2
catecholaminergic polymorphic ventricular tachycardia 1
ENSMUSG00000021313 (Ensembl Gene Model)
ENSMUSP00000021750 (Ensembl)
ENSMUST00000021750 (Ensembl)
rat Ryr2 689560 (Entrez Gene)
Chr17 q12.1 B0LPN4 (UniProt | EBI)
NM_032078 (RefSeq)
chimpanzee RYR2 457846 (Entrez Gene)
Chr1 XP_016797018 (RefSeq)
cattle RYR2 537376 (Entrez Gene)
Chr28 XP_015316426 (RefSeq)
dog RYR2 403615 (Entrez Gene)
Chr4 XP_022273677 (RefSeq)
chicken RYR2 421508 (Entrez Gene)
Chr3 XP_025004813 (RefSeq)
zebrafish ryr1a 798565 (Entrez Gene)
Chr10 XP_021327993 (RefSeq)
ryr1b 570245 (Entrez Gene)
Chr18 NP_001096041 (RefSeq)
NM_001102571 (RefSeq)
frog, western clawed ryr1 100495378 (Entrez Gene)
Chr8 XP_012824471 (RefSeq)
macaque, rhesus RYR2 717179 (Entrez Gene)
Chr1 XP_014982099 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory