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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37423

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RYR2 HGNC:10484 (HGNC)
6262 (Entrez Gene)
180902 (OMIM)
Chr1 q43 Chr1:237042210-237833988 (+)
GRCh38
Arrhythmogenic Right Ventricular Dysplasia, Familial, 2; ARVD2
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1
Q92736 (UniProt | EBI)
NM_001035 (RefSeq)
mouse Ryr2 MGI:99685 (MGI)
20191 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 4.38 cM Chr13:11553103-12106945 (-)
GRCm38
Arrhythmogenic Right Ventricular Dysplasia, Familial, 2; ARVD2
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1
20191 (NCBI Gene Model)
E9Q401 (UniProt | EBI)
NM_023868 (RefSeq)
rat Ryr2 689560 (Entrez Gene)
Chr17 q12.1 B0LPN4 (UniProt | EBI)
NM_032078 (RefSeq)
chimpanzee RYR2 457846 (Entrez Gene)
Chr1 XP_514296 (RefSeq)
rhesus macaque RYR2 717179 (Entrez Gene)
Chr1 XP_002808310 (RefSeq)
cattle LOC537376 537376 (Entrez Gene)
Chr28 XP_001788342 (RefSeq)
dog RYR2 403615 (Entrez Gene)
Chr4 XP_005618836 (RefSeq)
chicken RYR2 421508 (Entrez Gene)
Chr3 XP_419553 (RefSeq)
western clawed frog ryr1 100495378 (Entrez Gene)
ChrUN XP_002939294 (RefSeq)
zebrafish ryr1a 798565 (Entrez Gene)
Chr10 XP_001923294 (RefSeq)
ryr1b 570245 (Entrez Gene)
Chr18 NP_001096041 (RefSeq)
NM_001102571 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory