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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PTGIS HGNC:9603 (HGNC)
5740 (Entrez Gene)
601699 (OMIM)
Prostacyclin synthase (MyGene.info)
HGNC homology
Chr20 q13.13 Chr20:49503874-49568170 (-)
essential hypertension
Q16647 (UniProt | EBI)
NM_000961 (RefSeq)
mouse Ptgis MGI:1097156 (MGI)
19223 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 87.22 cM Chr2:167203196-167240537 (-)
19223 (NCBI Gene Model)
O35074 (UniProt | EBI)
NM_008968 (RefSeq)
rat Ptgis 25527 (Entrez Gene)
Chr3 q42 Q62969 (UniProt | EBI)
NM_031557 (RefSeq)
chimpanzee PTGIS 458323 (Entrez Gene)
Chr20 XP_016793607 (RefSeq)
cattle PTGIS 282021 (Entrez Gene)
Chr13 Q29626 (UniProt | EBI)
NM_174444 (RefSeq)
dog PTGIS 100856661 (Entrez Gene)
Chr24 XP_022264661 (RefSeq)
zebrafish ptgis 559148 (Entrez Gene)
Chr6 F1RE08 (UniProt | EBI)
NM_001111160 (RefSeq)
frog, western clawed ptgis 100492372 (Entrez Gene)
Chr10 XP_002933228 (RefSeq)
macaque, rhesus PTGIS 703407 (Entrez Gene)
Chr10 XP_015004277 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory