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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LGI1 HGNC:6572 (HGNC)
9211 (Entrez Gene)
604619 (OMIM)
LGI1 (MyGene.info)
HGNC homology
Chr10 q23.33 Chr10:93757770-93798174 (+)
familial temporal lobe epilepsy 1
O95970 (UniProt | EBI)
NM_005097 (RefSeq)
mouse Lgi1 MGI:1861691 (MGI)
56839 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 32.9 cM Chr19:38264536-38312214 (+)
familial temporal lobe epilepsy 1
OTTMUSG00000016342 (VEGA)
OTTMUSP00000017555 (VEGA)
OTTMUST00000039287 (VEGA)
rat Lgi1 252892 (Entrez Gene)
Chr1 q53 Q8K4Y5 (UniProt | EBI)
NM_145769 (RefSeq)
chimpanzee LGI1 450619 (Entrez Gene)
Chr10 Q1EGL2 (UniProt | EBI)
NM_001071778 (RefSeq)
cattle LGI1 617080 (Entrez Gene)
Chr26 Q5E9T6 (UniProt | EBI)
NM_001046591 (RefSeq)
dog LGI1 477777 (Entrez Gene)
Chr28 XP_534971 (RefSeq)
chicken LGI1 423802 (Entrez Gene)
Chr6 NP_001038120 (RefSeq)
NM_001044655 (RefSeq)
zebrafish lgi1a 323011 (Entrez Gene)
Chr13 NP_955921 (RefSeq)
NM_199627 (RefSeq)
lgi1b 654829 (Entrez Gene)
Chr12 NP_001122241 (RefSeq)
NM_001128769 (RefSeq)
frog, western clawed lgi1 779819 (Entrez Gene)
Chr7 NP_001072366 (RefSeq)
NM_001078898 (RefSeq)
macaque, rhesus LGI1 700520 (Entrez Gene)
Chr9 NP_001247986 (RefSeq)
NM_001261057 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory