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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACE HGNC:2707 (HGNC)
1636 (Entrez Gene)
106180 (OMIM)
Angiotensin-converting enzyme (MyGene.info)
HGNC homology
Chr17 q23.3 Chr17:63477061-63498380 (+)
Alzheimer's disease
P12821 (UniProt | EBI)
NM_001178057 (RefSeq)
mouse Ace MGI:87874 (MGI)
11421 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 68.84 cM Chr11:105967945-105989964 (+)
OTTMUSG00000003113 (VEGA)
OTTMUSP00000003021 (VEGA)
OTTMUST00000006415 (VEGA)
rat Ace 24310 (Entrez Gene)
Chr10 q32.1 P47820 (UniProt | EBI)
NM_012544 (RefSeq)
chimpanzee ACE 449567 (Entrez Gene)
Chr17 Q9GLN7 (UniProt | EBI)
NM_001008995 (RefSeq)
cattle ACE 509484 (Entrez Gene)
Chr19 NP_001193597 (RefSeq)
NM_001206668 (RefSeq)
dog ACE 610668 (Entrez Gene)
Chr9 XP_003639297 (RefSeq)
chicken ACE 419953 (Entrez Gene)
Chr27 Q10751 (UniProt | EBI)
NM_001167732 (RefSeq)
zebrafish ace 565980 (Entrez Gene)
Chr12 XP_694336 (RefSeq)
frog, western clawed ace 100144634 (Entrez Gene)
Chr10 NP_001116882 (RefSeq)
NM_001123410 (RefSeq)
macaque, rhesus ACE 100428661 (Entrez Gene)
Chr16 XP_014975566 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory