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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37314

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ALPL HGNC:438 (HGNC)
249 (Entrez Gene)
171760 (OMIM)
Chr1 p36.12 Chr1:21508982-21578412 (+)
GRCh38
Hypophosphatasia, Adult
Hypophosphatasia, Childhood
Hypophosphatasia, Infantile
P05186 (UniProt | EBI)
NM_000478 (RefSeq)
mouse Alpl MGI:87983 (MGI)
11647 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 70.02 cM Chr4:137741733-137796384 (-)
GRCm38
Hypophosphatasia, Adult
Hypophosphatasia, Childhood
Hypophosphatasia, Infantile
OTTMUSG00000009805 (VEGA)
OTTMUSP00000010372 (VEGA)
OTTMUST00000022726 (VEGA)
rat Alpl 25586 (Entrez Gene)
Chr5 q36 P08289 (UniProt | EBI)
NM_013059 (RefSeq)
chimpanzee ALPL 456600 (Entrez Gene)
Chr1 XP_003307915 (RefSeq)
rhesus macaque ALPL 717809 (Entrez Gene)
Chr1 NP_001253798 (RefSeq)
NM_001266869 (RefSeq)
dog ALPL 403548 (Entrez Gene)
Chr2 NP_001184066 (RefSeq)
NM_001197137 (RefSeq)
chicken ALPL 396317 (Entrez Gene)
Chr21 Q92058 (UniProt | EBI)
NM_205360 (RefSeq)
zebrafish alp3 100330410 (Entrez Gene)
Chr2 NP_001265768 (RefSeq)
NM_001278839 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory