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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ALPL HGNC:438 (HGNC)
249 (Entrez Gene)
171760 (OMIM)
ALPL (MyGene.info)
HGNC homology
Chr1 p36.12 Chr1:21508982-21578412 (+)
adult hypophosphatasia
childhood hypophosphatasia
infantile hypophosphatasia
P05186 (UniProt | EBI)
NM_000478 (RefSeq)
mouse Alpl MGI:87983 (MGI)
11647 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 70.02 cM Chr4:137741733-137796384 (-)
adult hypophosphatasia
childhood hypophosphatasia
infantile hypophosphatasia
OTTMUSG00000009805 (VEGA)
OTTMUSP00000010372 (VEGA)
OTTMUST00000022726 (VEGA)
rat Alpl 25586 (Entrez Gene)
Chr5 q36 P08289 (UniProt | EBI)
NM_013059 (RefSeq)
chimpanzee ALPL 456600 (Entrez Gene)
Chr1 XP_016811328 (RefSeq)
cattle ALPL 280994 (Entrez Gene)
Chr2 P09487 (UniProt | EBI)
NM_176858 (RefSeq)
dog ALPL 403548 (Entrez Gene)
Chr2 NP_001184066 (RefSeq)
NM_001197137 (RefSeq)
chicken ALPL 396317 (Entrez Gene)
Chr21 Q92058 (UniProt | EBI)
NM_205360 (RefSeq)
zebrafish alp3 100330410 (Entrez Gene)
Chr15 NP_001265768 (RefSeq)
NM_001278839 (RefSeq)
frog, western clawed alpl 100485467 (Entrez Gene)
ChrUN XP_002943485 (RefSeq)
macaque, rhesus ALPL 717809 (Entrez Gene)
Chr1 NP_001253798 (RefSeq)
NM_001266869 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory