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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PKLR HGNC:9020 (HGNC)
5313 (Entrez Gene)
609712 (OMIM)
PKLR (MyGene.info)
HGNC homology
Chr1 q22 Chr1:155289293-155301434 (-)
pyruvate kinase deficiency of red cells
P30613 (UniProt | EBI)
NM_181871 (RefSeq)
mouse Pklr MGI:97604 (MGI)
18770 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 39.01 cM Chr3:89136142-89146784 (+)
pyruvate kinase deficiency of red cells
OTTMUSG00000017504 (VEGA)
OTTMUSP00000019089 (VEGA)
OTTMUST00000042489 (VEGA)
rat Pklr 24651 (Entrez Gene)
Chr2 q34 P12928 (UniProt | EBI)
NM_012624 (RefSeq)
chimpanzee PKLR 469513 (Entrez Gene)
Chr1 XP_016784244 (RefSeq)
cattle PKLR 539579 (Entrez Gene)
Chr3 NP_001069644 (RefSeq)
NM_001076176 (RefSeq)
dog PKLR 490425 (Entrez Gene)
Chr7 Q29536 (UniProt | EBI)
NM_001256262 (RefSeq)
zebrafish pklr 114551 (Entrez Gene)
Chr16 NP_958446 (RefSeq)
NM_201289 (RefSeq)
macaque, rhesus PKLR 719152 (Entrez Gene)
Chr1 XP_014966895 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory