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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MTR HGNC:7468 (HGNC)
4548 (Entrez Gene)
156570 (OMIM)
Methionine synthase (MyGene.info)
HGNC homology
Chr1 q43 Chr1:236794304-236903981 (+)
neural tube defect
Q99707 (UniProt | EBI)
NM_000254 (RefSeq)
mouse Mtr MGI:894292 (MGI)
238505 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 4.52 cM Chr13:12182712-12258113 (-)
ENSMUSG00000021311 (Ensembl Gene Model)
ENSMUSP00000097442 (Ensembl)
ENSMUST00000099856 (Ensembl)
rat Mtr 81522 (Entrez Gene)
Chr17 q12.1 Q9Z2Q4 (UniProt | EBI)
NM_030864 (RefSeq)
chimpanzee MTR 457844 (Entrez Gene)
Chr1 XP_016796994 (RefSeq)
cattle MTR 280869 (Entrez Gene)
Chr28 Q4JIJ3 (UniProt | EBI)
NM_001030298 (RefSeq)
dog MTR 479190 (Entrez Gene)
Chr4 XP_005618842 (RefSeq)
chicken MTR 422069 (Entrez Gene)
Chr3 NP_001026275 (RefSeq)
NM_001031104 (RefSeq)
zebrafish mtr 378847 (Entrez Gene)
Chr12 NP_932338 (RefSeq)
NM_198072 (RefSeq)
frog, western clawed mtr 100488827 (Entrez Gene)
Chr5 XP_002933914 (RefSeq)
macaque, rhesus MTR 717582 (Entrez Gene)
Chr1 XP_014982532 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory