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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CACNA1S HGNC:1397 (HGNC)
779 (Entrez Gene)
114208 (OMIM)
Cav1.1 (MyGene.info)
HGNC homology
Chr1 q32.1 Chr1:201039509-201112566 (-)
hypokalemic periodic paralysis
malignant hyperthermia
Q13698 (UniProt | EBI)
NM_000069 (RefSeq)
mouse Cacna1s MGI:88294 (MGI)
12292 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 59.55 cM Chr1:136052750-136119535 (+)
hypokalemic periodic paralysis
OTTMUSG00000033761 (VEGA)
OTTMUSP00000045913 (VEGA)
OTTMUST00000085066 (VEGA)
rat Cacna1s 682930 (Entrez Gene)
Chr13 Q02485 (UniProt | EBI)
NM_053873 (RefSeq)
chimpanzee CACNA1S 469635 (Entrez Gene)
Chr1 XP_016790956 (RefSeq)
cattle CACNA1S 100337204 (Entrez Gene)
Chr16 XP_024832343 (RefSeq)
dog CACNA1S 490244 (Entrez Gene)
Chr7 XP_005622323 (RefSeq)
chicken CACNA1S 395985 (Entrez Gene)
Chr26 O42398 (UniProt | EBI)
NM_001305147 (RefSeq)
zebrafish cacna1sa 570683 (Entrez Gene)
Chr22 NP_001139622 (RefSeq)
NM_001146150 (RefSeq)
cacna1sb 405791 (Entrez Gene)
Chr8 NP_999891 (RefSeq)
NM_214726 (RefSeq)
macaque, rhesus CACNA1S 708706 (Entrez Gene)
Chr1 XP_014975975 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory