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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ADA HGNC:186 (HGNC)
100 (Entrez Gene)
608958 (OMIM)
Chr20 q13.12 Chr20:44619519-44651735 (-)
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Negative, Due to Adenosine Deaminase Deficiency
P00813 (UniProt | EBI)
NM_000022 (RefSeq)
mouse Ada MGI:87916 (MGI)
11486 (Entrez Gene)
Gene Tree
Chr2 84.44 cM Chr2:163726584-163750239 (-)
Priapism, Familial Idiopathic
OTTMUSG00000001154 (VEGA)
OTTMUSP00000001096 (VEGA)
OTTMUST00000002247 (VEGA)
rat Ada 24165 (Entrez Gene)
Chr3 q42 Q920P6 (UniProt | EBI)
NM_130399 (RefSeq)
chimpanzee ADA 741760 (Entrez Gene)
Chr20 XP_001144517 (RefSeq)
rhesus macaque ADA 717897 (Entrez Gene)
Chr10 XP_001109908 (RefSeq)
cattle ADA 280712 (Entrez Gene)
Chr13 P56658 (UniProt | EBI)
NM_173887 (RefSeq)
dog ADA 477236 (Entrez Gene)
Chr24 XP_005635154 (RefSeq)
chicken ADA 419194 (Entrez Gene)
Chr20 Q5ZKP6 (UniProt | EBI)
NM_001006290 (RefSeq)
western clawed frog ada 496434 (Entrez Gene)
ChrUN Q63ZU0 (UniProt | EBI)
NM_001011025 (RefSeq)
zebrafish ada 436919 (Entrez Gene)
Chr23 Q6DG22 (UniProt | EBI)
NM_001002646 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.20
The Jackson Laboratory