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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human A2M HGNC:7 (HGNC)
2 (Entrez Gene)
103950 (OMIM)
HGNC homology
Chr12 p13.31 Chr12:9067708-9115962 (-)
Alzheimer's disease
P01023 (UniProt | EBI)
NM_000014 (RefSeq)
mouse A2m MGI:2449119 (MGI)
232345 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 57.49 cM Chr6:121635376-121679227 (+)
OTTMUSG00000056872 (VEGA)
OTTMUSP00000073543 (VEGA)
OTTMUST00000140274 (VEGA)
rat A2m 24153 (Entrez Gene)
Chr4 q42 P06238 (UniProt | EBI)
NM_012488 (RefSeq)
LOC100911545 100911545 (Entrez Gene)
Chr4 XP_003749876 (RefSeq)
chimpanzee A2M 465372 (Entrez Gene)
Chr12 XP_009423065 (RefSeq)
cattle A2M 513856 (Entrez Gene)
Chr5 Q7SIH1 (UniProt | EBI)
NM_001109795 (RefSeq)
dog LOC477699 477699 (Entrez Gene)
Chr27 XP_534893 (RefSeq)
chicken A2M 418251 (Entrez Gene)
Chr1 XP_015148167 (RefSeq)
zebrafish a2ml 100006972 (Entrez Gene)
Chr15 NP_001132951 (RefSeq)
NM_001139479 (RefSeq)
LOC569025 569025 (Entrez Gene)
Chr15 XP_697477 (RefSeq)
LOC100006895 100006895 (Entrez Gene)
Chr15 XP_001923676 (RefSeq)
sb:cb37 100006947 (Entrez Gene)
si:ch211-212c13.8 100006925 (Entrez Gene)
si:ch211-212c13.10 100003785 (Entrez Gene)
Chr15 XP_021322080 (RefSeq)
si:dkey-46g23.2 793100 (Entrez Gene)
Chr3 XP_021327775 (RefSeq)
si:dkey-46g23.5 562067 (Entrez Gene)
Chr3 NP_001188334 (RefSeq)
NM_001201405 (RefSeq)
si:dkey-52d15.2 100006993 (Entrez Gene)
Chr15 XP_021322235 (RefSeq)
si:dkey-105h12.2 100006782 (Entrez Gene)
Chr15 XP_001345438 (RefSeq)
zgc:165453 566238 (Entrez Gene)
Chr3 XP_009297326 (RefSeq)
NM_001100950 (RefSeq)
zgc:165518 100101650 (Entrez Gene)
Chr3 NP_001093623 (RefSeq)
NM_001100153 (RefSeq)
zgc:171426 100137103 (Entrez Gene)
Chr3 XP_017210396 (RefSeq)
NM_001114700 (RefSeq)
zgc:171445 793035 (Entrez Gene)
Chr3 NP_001107101 (RefSeq)
NM_001113629 (RefSeq)
zgc:171446 100136837 (Entrez Gene)
Chr3 NP_001108028 (RefSeq)
NM_001114556 (RefSeq)
frog, western clawed a2m 619586 (Entrez Gene)
ChrUN XP_012809557 (RefSeq)
LOC100489060 100489060 (Entrez Gene)
ChrUN XP_002938549 (RefSeq)
macaque, rhesus A2M 716834 (Entrez Gene)
Chr11 XP_015006524 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory