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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MVK HGNC:7530 (HGNC)
4598 (Entrez Gene)
251170 (OMIM)
Mevalonate kinase (MyGene.info)
HGNC homology
Chr12 q24.11 Chr12:109573285-109597270 (+)
mevalonic aciduria
Q03426 (UniProt | EBI)
NM_001301182 (RefSeq)
mouse Mvk MGI:107624 (MGI)
17855 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 55.99 cM Chr5:114444269-114460591 (+)
OTTMUSG00000014479 (VEGA)
OTTMUSP00000015401 (VEGA)
OTTMUST00000034383 (VEGA)
rat Mvk 81727 (Entrez Gene)
Chr12 P17256 (UniProt | EBI)
NM_031063 (RefSeq)
chimpanzee MVK 467175 (Entrez Gene)
Chr12 XP_009424487 (RefSeq)
cattle MVK 505792 (Entrez Gene)
Chr17 Q5E9T8 (UniProt | EBI)
NM_001015528 (RefSeq)
dog MVK 486309 (Entrez Gene)
Chr26 XP_022266526 (RefSeq)
chicken LOC100857437 100857437 (Entrez Gene)
MVK 768555 (Entrez Gene)
Chr15 XP_015130996 (RefSeq)
zebrafish mvk 492477 (Entrez Gene)
Chr5 NP_001007350 (RefSeq)
NM_001007349 (RefSeq)
frog, western clawed mvk 100492928 (Entrez Gene)
Chr1 XP_012825244 (RefSeq)
macaque, rhesus MVK 707645 (Entrez Gene)
Chr11 XP_015008218 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory