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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP27B1 HGNC:2606 (HGNC)
1594 (Entrez Gene)
609506 (OMIM)
HGNC homology
Chr12 q14.1 Chr12:57762334-57767193 (-)
Vitamin D Hydroxylation-Deficient Rickets, Type 1A; VDDR1A
O15528 (UniProt | EBI)
NM_000785 (RefSeq)
mouse Cyp27b1 MGI:1098274 (MGI)
13115 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 74.5 cM Chr10:127048250-127053006 (+)
Vitamin D Hydroxylation-Deficient Rickets, Type 1A; VDDR1A
OTTMUSG00000035227 (VEGA)
OTTMUSP00000049096 (VEGA)
OTTMUST00000089781 (VEGA)
rat Cyp27b1 114700 (Entrez Gene)
Chr7 O35132 (UniProt | EBI)
NM_053763 (RefSeq)
chimpanzee LOC452027 452027 (Entrez Gene)
Chr12 XP_509175 (RefSeq)
rhesus macaque CYP27B1 715747 (Entrez Gene)
Chr11 NP_001181642 (RefSeq)
NM_001194713 (RefSeq)
cattle CYP27B1 539630 (Entrez Gene)
Chr5 NP_001179213 (RefSeq)
NM_001192284 (RefSeq)
dog CYP27B1 481133 (Entrez Gene)
Chr10 XP_538254 (RefSeq)
western clawed frog cyp27b1 448754 (Entrez Gene)
ChrUN NP_001006907 (RefSeq)
NM_001006906 (RefSeq)
zebrafish LOC793309 793309 (Entrez Gene)
Chr11 XP_003199448 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory