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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PITX3 HGNC:9006 (HGNC)
5309 (Entrez Gene)
602669 (OMIM)
PITX3 (MyGene.info)
HGNC homology
Chr10 q24.32 Chr10:102230189-102241474 (-)
anterior segment mesenchymal dysgenesis
cataract 11 multiple types
O75364 (UniProt | EBI)
NM_005029 (RefSeq)
mouse Pitx3 MGI:1100498 (MGI)
18742 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 38.75 cM Chr19:46135685-46148326 (-)
anterior segment mesenchymal dysgenesis
Parkinson's disease
OTTMUSG00000021234 (VEGA)
OTTMUSP00000023460 (VEGA)
OTTMUST00000050294 (VEGA)
rat Pitx3 29609 (Entrez Gene)
Chr1 q54 P81062 (UniProt | EBI)
NM_019247 (RefSeq)
chimpanzee PITX3 466189 (Entrez Gene)
Chr10 XP_016774698 (RefSeq)
cattle PITX3 512000 (Entrez Gene)
Chr26 NP_001179234 (RefSeq)
NM_001192305 (RefSeq)
dog PITX3 486856 (Entrez Gene)
Chr28 XP_013964434 (RefSeq)
chicken PITX3 423756 (Entrez Gene)
Chr6 XP_421631 (RefSeq)
zebrafish pitx3 402974 (Entrez Gene)
Chr13 Q6QU75 (UniProt | EBI)
NM_205675 (RefSeq)
frog, western clawed pitx3 100496690 (Entrez Gene)
Chr7 XP_002935807 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory