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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
3689

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PITX3 HGNC:9006 (HGNC)
5309 (Entrez Gene)
602669 (OMIM)
Chr10 q24.32 Chr10:102230189-102241474 (-)
GRCh38
Anterior Segment Mesenchymal Dysgenesis; ASMD
Cataract 11, Multiple Types; CTRCT11
O75364 (UniProt | EBI)
NM_005029 (RefSeq)
mouse Pitx3 MGI:1100498 (MGI)
18742 (Entrez Gene)
Gene Tree
VISTA-Point
Chr19 38.75 cM Chr19:46135685-46148326 (-)
GRCm38
Anterior Segment Mesenchymal Dysgenesis; ASMD
OTTMUSG00000021234 (VEGA)
OTTMUSP00000023460 (VEGA)
OTTMUST00000050294 (VEGA)
rat Pitx3 29609 (Entrez Gene)
Chr1 q54 P81062 (UniProt | EBI)
NM_019247 (RefSeq)
chimpanzee PITX3 466189 (Entrez Gene)
Chr10 XP_521591 (RefSeq)
cattle PITX3 512000 (Entrez Gene)
Chr26 NP_001179234 (RefSeq)
NM_001192305 (RefSeq)
dog PITX3 486856 (Entrez Gene)
Chr28 XP_005637719 (RefSeq)
chicken PITX3 423756 (Entrez Gene)
Chr6 XP_421631 (RefSeq)
western clawed frog pitx3 100496690 (Entrez Gene)
ChrUN XP_002935807 (RefSeq)
zebrafish pitx3 402974 (Entrez Gene)
Chr13 Q6QU75 (UniProt | EBI)
NM_205675 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory