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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PFN1 HGNC:8881 (HGNC)
5216 (Entrez Gene)
176610 (OMIM)
Profilin 1 (MyGene.info)
HGNC homology
Chr17 p13.2 Chr17:4945650-4949088 (-)
amyotrophic lateral sclerosis type 18
P07737 (UniProt | EBI)
NM_005022 (RefSeq)
mouse Pfn1 MGI:97549 (MGI)
18643 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 43.21 cM Chr11:70651850-70654644 (-)
OTTMUSG00000006068 (VEGA)
OTTMUSP00000006342 (VEGA)
OTTMUST00000013681 (VEGA)
rat Pfn1 64303 (Entrez Gene)
Chr10 q24 P62963 (UniProt | EBI)
NM_022511 (RefSeq)
chimpanzee PFN1 748477 (Entrez Gene)
Chr17 XP_009429954 (RefSeq)
cattle PFN1 513895 (Entrez Gene)
Chr19 P02584 (UniProt | EBI)
NM_001015592 (RefSeq)
macaque, rhesus PFN1 710753 (Entrez Gene)
Chr16 XP_014973845 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory