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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
3657

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MECP2 HGNC:6990 (HGNC)
4204 (Entrez Gene)
300005 (OMIM)
ChrX q28 ChrX:154021800-154097731 (-)
GRCh38
Angelman Syndrome; AS
Autism, Susceptibility to, X-Linked 3; AUTSX3
Encephalopathy, Neonatal Severe, Due to Mecp2 Mutations
Lubs X-Linked Mental Retardation Syndrome; MRXSL
Mental Retardation, X-Linked, Syndromic 13; MRXS13
Rett Syndrome; RTT
P51608 (UniProt | EBI)
NM_004992 (RefSeq)
mouse Mecp2 MGI:99918 (MGI)
17257 (Entrez Gene)
Gene Tree
VISTA-Point
ChrX 37.63 cM ChrX:74026592-74085690 (-)
GRCm38
Rett Syndrome; RTT
OTTMUSG00000017654 (VEGA)
OTTMUSP00000019680 (VEGA)
OTTMUST00000043832 (VEGA)
rat Mecp2 29386 (Entrez Gene)
ChrX Q00566 (UniProt | EBI)
NM_022673 (RefSeq)
chimpanzee MECP2 465936 (Entrez Gene)
ChrX XP_521333 (RefSeq)
rhesus macaque MECP2 700174 (Entrez Gene)
ChrX NP_001244471 (RefSeq)
NM_001257542 (RefSeq)
cattle MECP2 539629 (Entrez Gene)
ChrX NP_001193481 (RefSeq)
NM_001206552 (RefSeq)
dog MECP2 612973 (Entrez Gene)
ChrX XP_853488 (RefSeq)
western clawed frog mecp2 100216110 (Entrez Gene)
ChrUN NP_001135563 (RefSeq)
NM_001142091 (RefSeq)
zebrafish mecp2 335250 (Entrez Gene)
Chr8 NP_997901 (RefSeq)
NM_212736 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory