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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IDE HGNC:5381 (HGNC)
3416 (Entrez Gene)
146680 (OMIM)
Insulin-degrading enzyme (MyGene.info)
HGNC homology
Chr10 q23.33 Chr10:92451684-92574484 (-)
P14735 (UniProt | EBI)
NM_001322797 (RefSeq)
mouse Ide MGI:96412 (MGI)
15925 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 32.24 cM Chr19:37268743-37337852 (-)
OTTMUSG00000029864 (VEGA)
OTTMUSP00000038463 (VEGA)
OTTMUST00000074112 (VEGA)
rat Ide 25700 (Entrez Gene)
Chr1 q53 P35559 (UniProt | EBI)
NM_013159 (RefSeq)
chimpanzee IDE 450608 (Entrez Gene)
Chr10 XP_024202247 (RefSeq)
cattle IDE 523752 (Entrez Gene)
Chr26 Q24K02 (UniProt | EBI)
NM_001075849 (RefSeq)
dog IDE 477768 (Entrez Gene)
Chr28 NP_001301029 (RefSeq)
NM_001314100 (RefSeq)
chicken IDE 423814 (Entrez Gene)
Chr6 XP_004942214 (RefSeq)
zebrafish ide 561390 (Entrez Gene)
Chr13 NP_001082994 (RefSeq)
NM_001089525 (RefSeq)
frog, western clawed ide 100490154 (Entrez Gene)
Chr7 XP_002939138 (RefSeq)
macaque, rhesus IDE 698640 (Entrez Gene)
Chr9 NP_001245003 (RefSeq)
NM_001258074 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory