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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CISD2 HGNC:24212 (HGNC)
493856 (Entrez Gene)
611507 (OMIM)
HGNC homology
Chr4 q24 Chr4:102868978-102892807 (+)
Wolfram syndrome 2
Q8N5K1 (UniProt | EBI)
NM_001008388 (RefSeq)
mouse Cisd2 MGI:1914256 (MGI)
67006 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 62.55 cM Chr3:135406412-135423925 (-)
Wolfram syndrome 2
OTTMUSG00000029490 (VEGA)
OTTMUSP00000037790 (VEGA)
OTTMUST00000073072 (VEGA)
rat Cisd2 295457 (Entrez Gene)
Chr2 q43 NP_001178537 (RefSeq)
NM_001191608 (RefSeq)
chimpanzee CISD2 100609495 (Entrez Gene)
Chr4 XP_009446349 (RefSeq)
cattle CISD2 781260 (Entrez Gene)
Chr6 Q05B71 (UniProt | EBI)
NM_001080338 (RefSeq)
chicken CISD2 422714 (Entrez Gene)
Chr4 XP_420668 (RefSeq)
zebrafish cisd2 393354 (Entrez Gene)
Chr1 Q7T326 (UniProt | EBI)
NM_200383 (RefSeq)
frog, western clawed cisd2 496970 (Entrez Gene)
Chr1 Q5I027 (UniProt | EBI)
NM_001011479 (RefSeq)
macaque, rhesus CISD2 100429989 (Entrez Gene)
Chr5 XP_014994381 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory