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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AFP HGNC:317 (HGNC)
174 (Entrez Gene)
104150 (OMIM)
Chr4 q13.3 Chr4:73436219-73455785 (+)
Alpha-Fetoprotein Deficiency; AFPD
Alpha-Fetoprotein, Hereditary Persistence Of; HPAFP
P02771 (UniProt | EBI)
NM_001134 (RefSeq)
mouse Afp MGI:87951 (MGI)
11576 (Entrez Gene)
Gene Tree
Chr5 44.77 cM Chr5:90490714-90508907 (+)
11576 (NCBI Gene Model)
P02772 (UniProt | EBI)
NM_007423 (RefSeq)
rat Afp 24177 (Entrez Gene)
Chr14 p21 P02773 (UniProt | EBI)
NM_012493 (RefSeq)
chimpanzee AFP 461258 (Entrez Gene)
Chr4 XP_009446020 (RefSeq)
rhesus macaque AFP 704786 (Entrez Gene)
Chr5 XP_001103873 (RefSeq)
cattle AFP 506011 (Entrez Gene)
Chr6 Q3SZ57 (UniProt | EBI)
NM_001034262 (RefSeq)
dog AFP 403551 (Entrez Gene)
Chr13 Q8MJU5 (UniProt | EBI)
NM_001003027 (RefSeq)
chicken AFP 422652 (Entrez Gene)
Chr4 P84407 (UniProt | EBI)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory