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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRAK3 HGNC:17020 (HGNC)
11213 (Entrez Gene)
604459 (OMIM)
IRAK3 (MyGene.info)
HGNC homology
Chr12 q14.3 Chr12:66189198-66254622 (+)
Q9Y616 (UniProt | EBI)
NM_001142523 (RefSeq)
mouse Irak3 MGI:1921164 (MGI)
73914 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 67.94 cM Chr10:120141648-120201744 (-)
type 1 diabetes mellitus
73914 (NCBI Gene Model)
Q8K4B2 (UniProt | EBI)
NR_152856 (RefSeq)
rat Irak3 314870 (Entrez Gene)
Chr7 q22 NP_001101571 (RefSeq)
NM_001108101 (RefSeq)
chimpanzee IRAK3 467058 (Entrez Gene)
Chr12 XP_009423256 (RefSeq)
cattle IRAK3 510342 (Entrez Gene)
Chr5 NP_001177228 (RefSeq)
NM_001190299 (RefSeq)
dog IRAK3 481150 (Entrez Gene)
Chr10 XP_005625714 (RefSeq)
zebrafish irak3 567444 (Entrez Gene)
Chr4 XP_017210784 (RefSeq)
macaque, rhesus IRAK3 717845 (Entrez Gene)
Chr11 XP_002798715 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory