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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
36179

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SH2B3 HGNC:29605 (HGNC)
10019 (Entrez Gene)
605093 (OMIM)
Chr12 q24 Chr12:111405917-111451623 (+)
GRCh38
Erythrocytosis, Familial, 1; ECYT1
Myelofibrosis
Thrombocythemia 1; THCYT1
Q9UQQ2 (UniProt | EBI)
NM_005475 (RefSeq)
mouse Sh2b3 MGI:893598 (MGI)
16923 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 61.99 cM Chr5:121815488-121836859 (-)
GRCm38
OTTMUSG00000029807 (VEGA)
OTTMUSP00000038367 (VEGA)
OTTMUST00000073987 (VEGA)
chimpanzee SH2B3 452245 (Entrez Gene)
Chr12 XP_001145612 (RefSeq)
rhesus macaque SH2B3 710839 (Entrez Gene)
Chr11 XP_001108790 (RefSeq)
cattle SH2B3 614726 (Entrez Gene)
Chr17 NP_001179996 (RefSeq)
NM_001193067 (RefSeq)
dog SH2B3 100683018 (Entrez Gene)
Chr26 XP_003433461 (RefSeq)
chicken SH2B3 416876 (Entrez Gene)
Chr15 XP_003642242 (RefSeq)
western clawed frog sh2b3 100101733 (Entrez Gene)
ChrUN NP_001093717 (RefSeq)
NM_001100247 (RefSeq)
zebrafish LOC101884640 101884640 (Entrez Gene)
Chr5 XP_005162520 (RefSeq)
sh2b3 573284 (Entrez Gene)
Chr5 XP_003198643 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory