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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human VAPB HGNC:12649 (HGNC)
9217 (Entrez Gene)
605704 (OMIM)
Chr20 q13.33 Chr20:58389119-58451101 (+)
Amyotrophic Lateral Sclerosis 8; ALS8
Spinal Muscular Atrophy, Late-Onset, Finkel Type; SMAFK
O95292 (UniProt | EBI)
NM_004738 (RefSeq)
mouse Vapb MGI:1928744 (MGI)
56491 (Entrez Gene)
Gene Tree
Chr2 97.37 cM Chr2:173737511-173784336 (+)
Amyotrophic Lateral Sclerosis 8; ALS8
OTTMUSG00000016375 (VEGA)
OTTMUSP00000017608 (VEGA)
OTTMUST00000039412 (VEGA)
rat Vapb 60431 (Entrez Gene)
Chr3 q42 Q9Z269 (UniProt | EBI)
NM_021847 (RefSeq)
chimpanzee VAPB 469984 (Entrez Gene)
Chr20 XP_001135464 (RefSeq)
cattle VAPB 326580 (Entrez Gene)
Chr13 A2VDZ9 (UniProt | EBI)
NM_001082423 (RefSeq)
dog VAPB 477274 (Entrez Gene)
Chr24 XP_534466 (RefSeq)
chicken VAPB 419317 (Entrez Gene)
Chr20 NP_001006296 (RefSeq)
NM_001006296 (RefSeq)
western clawed frog MGC76271 394500 (Entrez Gene)
ChrUN NP_988905 (RefSeq)
NM_203574 (RefSeq)
zebrafish vapb 323628 (Entrez Gene)
Chr6 NP_997812 (RefSeq)
NM_212647 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory