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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NLRP3 HGNC:16400 (HGNC)
114548 (Entrez Gene)
606416 (OMIM)
HGNC homology
Chr1 q44 Chr1:247415904-247449108 (+)
Familial Cold Autoinflammatory Syndrome 1; FCAS1
Muckle-Wells Syndrome; MWS
Q96P20 (UniProt | EBI)
NM_001127461 (RefSeq)
mouse Nlrp3 MGI:2653833 (MGI)
216799 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 37.73 cM Chr11:59541568-59566955 (+)
Familial Cold Autoinflammatory Syndrome 1; FCAS1
Muckle-Wells Syndrome; MWS
OTTMUSG00000005801 (VEGA)
OTTMUSP00000005970 (VEGA)
OTTMUST00000012840 (VEGA)
rat Nlrp3 287362 (Entrez Gene)
Chr10 q22 NP_001178571 (RefSeq)
NM_001191642 (RefSeq)
chimpanzee NLRP3 469743 (Entrez Gene)
Chr1 XP_016797757 (RefSeq)
rhesus macaque NLRP3 701278 (Entrez Gene)
Chr1 B0FPE9 (UniProt | EBI)
NM_001114351 (RefSeq)
cattle NLRP3 538639 (Entrez Gene)
Chr7 A6QLE5 (UniProt | EBI)
NM_001102219 (RefSeq)
dog NLRP3 490576 (Entrez Gene)
Chr8 XP_848377 (RefSeq)
chicken NLRP3 423021 (Entrez Gene)
Chr5 XP_015141766 (RefSeq)
NM_001031178 (RefSeq)
western clawed frog LOC100486578 100486578 (Entrez Gene)
ChrUN XP_012825310 (RefSeq)
LOC100486737 100486737 (Entrez Gene)
ChrUN XP_002937318 (RefSeq)
LOC100487412 100487412 (Entrez Gene)
ChrUN XP_002938247 (RefSeq)
LOC100488643 100488643 (Entrez Gene)
ChrUN XP_012825308 (RefSeq)
LOC100488807 100488807 (Entrez Gene)
ChrUN XP_002943171 (RefSeq)
LOC100488969 100488969 (Entrez Gene)
LOC100489137 100489137 (Entrez Gene)
ChrUN XP_002943173 (RefSeq)
LOC100491706 100491706 (Entrez Gene)
ChrUN XP_002944439 (RefSeq)
LOC100493406 100493406 (Entrez Gene)
ChrUN XP_012825346 (RefSeq)
LOC100495083 100495083 (Entrez Gene)
LOC101730480 101730480 (Entrez Gene)
ChrUN XP_012825347 (RefSeq)
LOC101730774 101730774 (Entrez Gene)
LOC101730849 101730849 (Entrez Gene)
ChrUN XP_012825341 (RefSeq)
LOC101730955 101730955 (Entrez Gene)
ChrUN XP_004917628 (RefSeq)
LOC101731251 101731251 (Entrez Gene)
ChrUN XP_012810990 (RefSeq)
nlrp3 100497524 (Entrez Gene)
ChrUN XP_002945565 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.05
The Jackson Laboratory