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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human OTOP1 HGNC:19656 (HGNC)
133060 (Entrez Gene)
607806 (OMIM)
HGNC homology
Chr4 p16.3 Chr4:4188803-4226894 (-)
Q7RTM1 (UniProt | EBI)
NM_177998 (RefSeq)
mouse Otop1 MGI:2388363 (MGI)
21906 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 20.35 cM Chr5:38277404-38304217 (+)
21906 (NCBI Gene Model)
Q80VM9 (UniProt | EBI)
NM_172709 (RefSeq)
rat Otop1 305427 (Entrez Gene)
Chr14 q21 Q7M734 (UniProt | EBI)
NM_181433 (RefSeq)
chimpanzee OTOP1 471127 (Entrez Gene)
Chr4 XP_526509 (RefSeq)
cattle OTOP1 525643 (Entrez Gene)
Chr6 NP_001193713 (RefSeq)
NM_001206784 (RefSeq)
dog OTOP1 488825 (Entrez Gene)
Chr3 XP_545943 (RefSeq)
chicken OTOP1 422844 (Entrez Gene)
Chr4 XP_025005572 (RefSeq)
zebrafish otop1 322893 (Entrez Gene)
Chr14 Q7ZWK8 (UniProt | EBI)
NM_198803 (RefSeq)
frog, western clawed otop1 100495027 (Entrez Gene)
Chr1 XP_012811170 (RefSeq)
macaque, rhesus OTOP1 712780 (Entrez Gene)
Chr5 XP_001097009 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory