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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human USP53 HGNC:29255 (HGNC)
54532 (Entrez Gene)
617431 (OMIM)
USP53 (MyGene.info)
HGNC homology
Chr4 q26 Chr4:119212583-119295518 (+)
Q70EK8 (UniProt | EBI)
NM_019050 (RefSeq)
mouse Usp53 MGI:2139607 (MGI)
99526 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 53.75 cM Chr3:122931486-122984447 (-)
99526 (NCBI Gene Model)
P15975 (UniProt | EBI)
NM_133857 (RefSeq)
chimpanzee USP53 461457 (Entrez Gene)
Chr4 XP_016807609 (RefSeq)
cattle USP53 529462 (Entrez Gene)
dog USP53 487923 (Entrez Gene)
Chr32 XP_022269410 (RefSeq)
chicken USP53 422680 (Entrez Gene)
frog, western clawed usp53 100158512 (Entrez Gene)
Chr1 XP_002934301 (RefSeq)
macaque, rhesus USP53 705228 (Entrez Gene)
Chr5 XP_014994627 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory