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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TK2 HGNC:11831 (HGNC)
7084 (Entrez Gene)
188250 (OMIM)
HGNC homology
Chr16 q21 Chr16:66508003-66550412 (-)
mitochondrial DNA depletion syndrome 2
O00142 (UniProt | EBI)
NM_001172643 (RefSeq)
mouse Tk2 MGI:1913266 (MGI)
57813 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 53.04 cM Chr8:104226685-104248558 (-)
mitochondrial DNA depletion syndrome 2
ENSMUSG00000035824 (Ensembl Gene Model)
ENSMUSP00000053616 (Ensembl)
ENSMUST00000050211 (Ensembl)
rat Tk2 291824 (Entrez Gene)
Chr19 p14 NP_001099636 (RefSeq)
NM_001106166 (RefSeq)
chimpanzee TK2 454144 (Entrez Gene)
Chr16 XP_016785463 (RefSeq)
cattle TK2 615457 (Entrez Gene)
Chr18 XP_015331294 (RefSeq)
dog TK2 611387 (Entrez Gene)
Chr5 XP_022275113 (RefSeq)
chicken TK2 427551 (Entrez Gene)
Chr11 NP_001026631 (RefSeq)
NM_001031460 (RefSeq)
zebrafish tk2 437016 (Entrez Gene)
Chr7 NP_001002743 (RefSeq)
NM_001002743 (RefSeq)
frog, western clawed tk2 549642 (Entrez Gene)
Chr4 NP_001016888 (RefSeq)
NM_001016888 (RefSeq)
macaque, rhesus TK2 693544 (Entrez Gene)
Chr20 XP_001083029 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory