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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRKN HGNC:8607 (HGNC)
5071 (Entrez Gene)
602544 (OMIM)
Parkin (ligase) (MyGene.info)
HGNC homology
Chr6 q26 Chr6:161347417-162727802 (-)
lung cancer
ovarian cancer
Parkinson's disease 2
O60260 (UniProt | EBI)
NM_013987 (RefSeq)
mouse Prkn MGI:1355296 (MGI)
50873 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 7.8 cM Chr17:10840384-12063361 (+)
Parkinson's disease 2
ENSMUSG00000023826 (Ensembl Gene Model)
ENSMUSP00000140587 (Ensembl)
ENSMUST00000191124 (Ensembl)
rat Prkn 56816 (Entrez Gene)
Chr1 q11 Q9JK66 (UniProt | EBI)
NM_020093 (RefSeq)
chimpanzee PRKN 741350 (Entrez Gene)
Chr6 XP_009450628 (RefSeq)
cattle PRKN 530858 (Entrez Gene)
Chr9 NP_001185994 (RefSeq)
NM_001199065 (RefSeq)
dog PRKN 612316 (Entrez Gene)
Chr1 XP_855152 (RefSeq)
chicken PARK2 421577 (Entrez Gene)
Chr3 XP_419615 (RefSeq)
zebrafish prkn 550328 (Entrez Gene)
Chr13 NP_001017635 (RefSeq)
NM_001017635 (RefSeq)
macaque, rhesus PRKN 710899 (Entrez Gene)
Chr4 XP_014992816 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory