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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ERBB2 HGNC:3430 (HGNC)
2064 (Entrez Gene)
164870 (OMIM)
HER2/neu (MyGene.info)
HGNC homology
Chr17 q12 Chr17:39688084-39728662 (+)
lung cancer
stomach cancer
P04626 (UniProt | EBI)
NM_001005862 (RefSeq)
mouse Erbb2 MGI:95410 (MGI)
13866 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 61.75 cM Chr11:98412470-98437716 (+)
breast cancer
dilated cardiomyopathy
Hirschsprung's disease
OTTMUSG00000002711 (VEGA)
OTTMUSP00000002540 (VEGA)
OTTMUST00000005365 (VEGA)
rat Erbb2 24337 (Entrez Gene)
Chr10 q31 P06494 (UniProt | EBI)
NM_017003 (RefSeq)
chimpanzee ERBB2 454636 (Entrez Gene)
Chr17 XP_016786245 (RefSeq)
cattle ERBB2 505709 (Entrez Gene)
Chr19 NP_001290558 (RefSeq)
NM_001303629 (RefSeq)
dog ERBB2 403883 (Entrez Gene)
Chr9 O18735 (UniProt | EBI)
NM_001003217 (RefSeq)
chicken ERBB2 426130 (Entrez Gene)
Chr27 NP_001038126 (RefSeq)
NM_001044661 (RefSeq)
zebrafish erbb2 386966 (Entrez Gene)
Chr12 NP_956413 (RefSeq)
NM_200119 (RefSeq)
frog, western clawed erbb2 100492078 (Entrez Gene)
Chr10 XP_002940420 (RefSeq)
macaque, rhesus ERBB2 697573 (Entrez Gene)
Chr16 XP_001090430 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory