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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AIRE HGNC:360 (HGNC)
326 (Entrez Gene)
607358 (OMIM)
Autoimmune regulator (MyGene.info)
HGNC homology
Chr21 q22.3 Chr21:44285838-44298219 (+)
autoimmune polyendocrine syndrome type 1
O43918 (UniProt | EBI)
NM_000383 (RefSeq)
mouse Aire MGI:1338803 (MGI)
11634 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 39.72 cM Chr10:78030022-78043610 (-)
autoimmune polyendocrine syndrome type 1
Guillain-Barre syndrome
Sjogren's syndrome
OTTMUSG00000034126 (VEGA)
OTTMUSP00000046748 (VEGA)
OTTMUST00000086350 (VEGA)
rat Aire 294328 (Entrez Gene)
Chr20 p12 NP_001099849 (RefSeq)
NM_001106379 (RefSeq)
chimpanzee AIRE 474134 (Entrez Gene)
Chr21 XP_016794129 (RefSeq)
cattle AIRE 784775 (Entrez Gene)
Chr1 XP_024852485 (RefSeq)
dog AIRE 487796 (Entrez Gene)
Chr31 XP_022269032 (RefSeq)
zebrafish aire 100007662 (Entrez Gene)
Chr2 NP_001103484 (RefSeq)
NM_001110014 (RefSeq)
macaque, rhesus AIRE 712858 (Entrez Gene)
Chr3 XP_014988262 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory