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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPHP3 HGNC:7907 (HGNC)
27031 (Entrez Gene)
608002 (OMIM)
NPHP3 (MyGene.info)
HGNC homology
Chr3 q22.1 Chr3:132680609-132722459 (-)
Meckel syndrome 7
nephronophthisis 3
renal-hepatic-pancreatic dysplasia
Q7Z494 (UniProt | EBI)
NM_153240 (RefSeq)
mouse Nphp3 MGI:1921275 (MGI)
74025 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 56.11 cM Chr9:104002544-104043811 (+)
autosomal dominant polycystic kidney disease
nephronophthisis 3
74025 (NCBI Gene Model)
Q7TNH6 (UniProt | EBI)
NM_028721 (RefSeq)
rat Nphp3 363126 (Entrez Gene)
Chr8 q32 NP_001178811 (RefSeq)
NM_001191882 (RefSeq)
chimpanzee NPHP3 460706 (Entrez Gene)
Chr3 XP_024211454 (RefSeq)
cattle NPHP3 507522 (Entrez Gene)
Chr1 NP_001179081 (RefSeq)
NM_001192152 (RefSeq)
dog NPHP3 100856544 (Entrez Gene)
Chr23 XP_022264349 (RefSeq)
chicken NPHP3 420690 (Entrez Gene)
Chr2 XP_025003263 (RefSeq)
zebrafish nphp3 562601 (Entrez Gene)
Chr24 P0CI65 (UniProt | EBI)
NM_001202441 (RefSeq)
frog, western clawed nphp3 780190 (Entrez Gene)
Chr6 A0JM23 (UniProt | EBI)
NM_001079265 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory