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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GRHL2 HGNC:2799 (HGNC)
79977 (Entrez Gene)
608576 (OMIM)
HGNC homology
Chr8 q22.3 Chr8:101492440-101678105 (+)
autosomal dominant nonsyndromic deafness 28
Q6ISB3 (UniProt | EBI)
NM_024915 (RefSeq)
mouse Grhl2 MGI:2182543 (MGI)
252973 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 14.84 cM Chr15:37233036-37363569 (+)
OTTMUSG00000030880 (VEGA)
OTTMUSP00000040224 (VEGA)
OTTMUST00000076417 (VEGA)
rat Grhl2 299979 (Entrez Gene)
Chr7 q22 NP_001127999 (RefSeq)
NM_001134527 (RefSeq)
chimpanzee GRHL2 464320 (Entrez Gene)
Chr8 XP_519890 (RefSeq)
cattle GRHL2 519918 (Entrez Gene)
Chr14 XP_015321854 (RefSeq)
dog GRHL2 481985 (Entrez Gene)
Chr13 XP_022282299 (RefSeq)
chicken GRHL2 429506 (Entrez Gene)
Chr2 XP_004940036 (RefSeq)
zebrafish grhl2b 100034503 (Entrez Gene)
Chr19 NP_001076541 (RefSeq)
NM_001083072 (RefSeq)
frog, western clawed grhl2 496802 (Entrez Gene)
Chr6 Q5M7R9 (UniProt | EBI)
NM_001011338 (RefSeq)
macaque, rhesus GRHL2 706549 (Entrez Gene)
Chr8 XP_015001290 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory