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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MCPH1 HGNC:6954 (HGNC)
79648 (Entrez Gene)
607117 (OMIM)
HGNC homology
Chr8 p23.1 Chr8:6406592-6648505 (+)
primary autosomal recessive microcephaly 1
Q8NEM0 (UniProt | EBI)
NM_001322045 (RefSeq)
mouse Mcph1 MGI:2443308 (MGI)
244329 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 10.24 cM Chr8:18595131-18803189 (+)
ENSMUSG00000039842 (Ensembl Gene Model)
ENSMUSP00000037000 (Ensembl)
ENSMUST00000039412 (Ensembl)
rat Mcph1 306594 (Entrez Gene)
Chr16 q12.5 XP_006222346 (RefSeq)
chimpanzee MCPH1 449589 (Entrez Gene)
Chr8 P61593 (UniProt | EBI)
NM_001009010 (RefSeq)
cattle MCPH1 100125236 (Entrez Gene)
Chr27 NP_001096785 (RefSeq)
NM_001103315 (RefSeq)
dog MCPH1 442960 (Entrez Gene)
Chr16 NP_001003366 (RefSeq)
NM_001003366 (RefSeq)
chicken MCPH1 100125976 (Entrez Gene)
Chr3 NP_001098789 (RefSeq)
NM_001105319 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory