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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IFIH1 HGNC:18873 (HGNC)
64135 (Entrez Gene)
606951 (OMIM)
MDA5 (MyGene.info)
HGNC homology
Chr2 q24.2 Chr2:162267079-162318708 (-)
Aicardi-Goutieres syndrome
Q9BYX4 (UniProt | EBI)
NM_022168 (RefSeq)
mouse Ifih1 MGI:1918836 (MGI)
71586 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 35.85 cM Chr2:62595798-62646255 (-)
systemic lupus erythematosus
OTTMUSG00000012871 (VEGA)
OTTMUSP00000013829 (VEGA)
OTTMUST00000030862 (VEGA)
rat Ifih1 499801 (Entrez Gene)
Chr3 q21 NP_001102669 (RefSeq)
NM_001109199 (RefSeq)
chimpanzee IFIH1 459692 (Entrez Gene)
Chr2B XP_016805442 (RefSeq)
cattle IFIH1 535490 (Entrez Gene)
Chr2 XP_010824766 (RefSeq)
dog IFIH1 488371 (Entrez Gene)
Chr36 XP_545493 (RefSeq)
chicken IFIH1 424185 (Entrez Gene)
Chr7 NP_001180567 (RefSeq)
NM_001193638 (RefSeq)
zebrafish ifih1 565759 (Entrez Gene)
Chr9 NP_001295492 (RefSeq)
NM_001308563 (RefSeq)
frog, western clawed ifih1 100488298 (Entrez Gene)
Chr9 XP_002933320 (RefSeq)
macaque, rhesus IFIH1 702024 (Entrez Gene)
Chr12 NP_001040588 (RefSeq)
NM_001047123 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory