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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GSDME HGNC:2810 (HGNC)
1687 (Entrez Gene)
608798 (OMIM)
DFNA5 (MyGene.info)
HGNC homology
Chr7 p15.3 Chr7:24698355-24758020 (-)
autosomal dominant nonsyndromic deafness 5
O60443 (UniProt | EBI)
NM_004403 (RefSeq)
mouse Gsdme MGI:1889850 (MGI)
54722 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 24.13 cM Chr6:50207401-50262862 (-)
54722 (NCBI Gene Model)
Q9Z2D3 (UniProt | EBI)
NM_018769 (RefSeq)
rat Gsdme 353316 (Entrez Gene)
Chr4 q24 NP_001178678 (RefSeq)
NM_001191749 (RefSeq)
chimpanzee GSDME 463295 (Entrez Gene)
Chr7 XP_016812680 (RefSeq)
cattle GSDME 616398 (Entrez Gene)
Chr4 NP_001180041 (RefSeq)
NM_001193112 (RefSeq)
dog GSDME 611223 (Entrez Gene)
Chr14 XP_853956 (RefSeq)
chicken GSDME 420623 (Entrez Gene)
Chr2 NP_001006361 (RefSeq)
NM_001006361 (RefSeq)
zebrafish gsdmeb 335722 (Entrez Gene)
Chr16 NP_001001947 (RefSeq)
NM_001001947 (RefSeq)
frog, western clawed gsdme 100486029 (Entrez Gene)
Chr6 XP_012821030 (RefSeq)
macaque, rhesus GSDME 703441 (Entrez Gene)
Chr3 XP_001096330 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory