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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
3230

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NKX2-5 HGNC:2488 (HGNC)
1482 (Entrez Gene)
600584 (OMIM)
Chr5 q34 Chr5:173232104-173235312 (-)
GRCh38
Atrial Septal Defect 7 with or without Atrioventricular Conduction Defects; ASD7
Conotruncal Heart Malformations; CTHM
Hypoplastic Left Heart Syndrome 2; HLHS2
Hypothyroidism, Congenital, Nongoitrous, 2; CHNG2
Tetralogy of Fallot; TOF
Ventricular Septal Defect 3; VSD3
P52952 (UniProt | EBI)
NM_004387 (RefSeq)
mouse Nkx2-5 MGI:97350 (MGI)
18091 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 13.6 cM Chr17:26838664-26841565 (-)
GRCm38
OTTMUSG00000037537 (VEGA)
OTTMUSP00000054102 (VEGA)
OTTMUST00000096774 (VEGA)
rat Nkx2-5 114109 (Entrez Gene)
Chr10 q12 O35767 (UniProt | EBI)
NM_053651 (RefSeq)
chimpanzee NKX2-5 462273 (Entrez Gene)
Chr5 XP_518104 (RefSeq)
rhesus macaque NKX2-5 703795 (Entrez Gene)
Chr6 XP_001096796 (RefSeq)
cattle NKX2-5 538870 (Entrez Gene)
Chr20 NP_001039908 (RefSeq)
NM_001046443 (RefSeq)
dog NKX2-5 489113 (Entrez Gene)
Chr4 NP_001010959 (RefSeq)
NM_001010959 (RefSeq)
chicken NKX2-5 396073 (Entrez Gene)
Chr13 Q90788 (UniProt | EBI)
NM_205164 (RefSeq)
zebrafish nkx2.5 30696 (Entrez Gene)
Chr14 NP_571496 (RefSeq)
NM_131421 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory