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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GAMT HGNC:4136 (HGNC)
2593 (Entrez Gene)
601240 (OMIM)
HGNC homology
Chr19 p13.3 Chr19:1397026-1401570 (-)
guanidinoacetate methyltransferase deficiency
Q14353 (UniProt | EBI)
NM_000156 (RefSeq)
mouse Gamt MGI:1098221 (MGI)
14431 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 39.72 cM Chr10:80258151-80261012 (-)
guanidinoacetate methyltransferase deficiency
ENSMUSG00000020150 (Ensembl Gene Model)
ENSMUSP00000020359 (Ensembl)
ENSMUST00000020359 (Ensembl)
rat Gamt 25257 (Entrez Gene)
Chr7 q11 P10868 (UniProt | EBI)
NM_012793 (RefSeq)
chimpanzee GAMT 749982 (Entrez Gene)
Chr19 XP_016790054 (RefSeq)
cattle GAMT 515270 (Entrez Gene)
Chr7 Q2TBQ3 (UniProt | EBI)
NM_001038544 (RefSeq)
zebrafish gamt 796865 (Entrez Gene)
Chr11 Q71N41 (UniProt | EBI)
NM_001105595 (RefSeq)
frog, western clawed gamt 394491 (Entrez Gene)
Chr1 Q6PBF6 (UniProt | EBI)
NM_203565 (RefSeq)
macaque, rhesus GAMT 721263 (Entrez Gene)
Chr19 NP_001248061 (RefSeq)
NM_001261132 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory