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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ZIC4 HGNC:20393 (HGNC)
84107 (Entrez Gene)
608948 (OMIM)
HGNC homology
Chr3 q24 Chr3:147386048-147406893 (-)
Q8N9L1 (UniProt | EBI)
NM_001168378 (RefSeq)
mouse Zic4 MGI:107201 (MGI)
22774 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 48.26 cM Chr9:91362413-91389348 (+)
Dandy-Walker syndrome
OTTMUSG00000038052 (VEGA)
OTTMUSP00000055017 (VEGA)
OTTMUST00000098031 (VEGA)
chimpanzee ZIC4 470956 (Entrez Gene)
Chr3 XP_024211513 (RefSeq)
cattle ZIC4 539312 (Entrez Gene)
Chr1 XP_586391 (RefSeq)
dog ZIC4 485704 (Entrez Gene)
Chr23 XP_013962244 (RefSeq)
chicken ZIC4 424885 (Entrez Gene)
Chr9 XP_015147102 (RefSeq)
zebrafish zic4 767673 (Entrez Gene)
Chr24 NP_001070080 (RefSeq)
NM_001076612 (RefSeq)
frog, western clawed zic4 100493609 (Entrez Gene)
Chr5 XP_017949927 (RefSeq)
macaque, rhesus ZIC4 712982 (Entrez Gene)
Chr2 XP_001110894 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory