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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TGFBR1 HGNC:11772 (HGNC)
7046 (Entrez Gene)
190181 (OMIM)
HGNC homology
Chr9 q22 Chr9:99104038-99154192 (+)
Multiple Self-Healing Squamous Epithelioma, Susceptibility To; MSSE
P36897 (UniProt | EBI)
NM_001130916 (RefSeq)
mouse Tgfbr1 MGI:98728 (MGI)
21812 (Entrez Gene)
Gene Tree
Chr4 26.02 cM Chr4:47353222-47414931 (+)
Loeys-Dietz Syndrome 1; LDS1
Scleroderma, Familial Progressive
OTTMUSG00000006800 (VEGA)
OTTMUSP00000007205 (VEGA)
OTTMUST00000015672 (VEGA)
rat Tgfbr1 29591 (Entrez Gene)
Chr5 q22 P80204 (UniProt | EBI)
NM_012775 (RefSeq)
chimpanzee TGFBR1 472992 (Entrez Gene)
Chr9 XP_001159299 (RefSeq)
rhesus macaque TGFBR1 714952 (Entrez Gene)
Chr15 XP_001112621 (RefSeq)
cattle TGFBR1 282382 (Entrez Gene)
Chr8 O46680 (UniProt | EBI)
NM_174621 (RefSeq)
dog TGFBR1 481628 (Entrez Gene)
Chr11 XP_013973356 (RefSeq)
chicken TGFBR1 374094 (Entrez Gene)
Chr2 NP_989577 (RefSeq)
NM_204246 (RefSeq)
western clawed frog tgfbr1 548715 (Entrez Gene)
ChrUN NP_001015961 (RefSeq)
NM_001015961 (RefSeq)
zebrafish tgfbr1a 560578 (Entrez Gene)
Chr2 NP_001032772 (RefSeq)
NM_001037683 (RefSeq)
tgfbr1b 792928 (Entrez Gene)
Chr24 NP_001108531 (RefSeq)
NM_001115059 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory